Irf6 cancer
IRF6 gene has been observed progressively downregulated in Human papillomavirus-positive neoplastic keratinocytes derived from uterine cervical preneoplastic lesions at different levels of malignancy. For this reason, this gene is likely to be associated with tumorigenesis and may be a potential prognostic marker for uterine cervical preneoplastic lesions progression. Similarly, IRF6 has been found to be genetically and epigenetically disregulated in Vulvar cancer. WebIRF6 INFORMATION. Proteini. Full gene name according to HGNC. Interferon regulatory factor 6. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. IRF6 (LPS, OFC6, VWS, VWS1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s).
Irf6 cancer
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WebAug 23, 2013 · Authors. Venkatesh Babu Gurramkonda ; Jyotsna Murthy ; Altaf Hussain Syed ; Bhaskar VKS Lakkakula Sri Ramachandra University Porur, Chennai - 600 116, India ; DOI ... WebAug 4, 2024 · IRF6 expression in cervical cancer specimens and cell lines was significantly reduced compared to that in the corresponding control group. In addition, IRF6 expression was negatively correlated with miR‐587 in cervical cancer tissues. Bioinformatics algorithms and luciferase assays revealed that IRF6 is a potential target of miR‐587, and ...
WebJun 21, 2024 · The findings of this study indicate that IRF6 is downregulated in highly malignant human and mouse breast cancer cell lines. Also, the modulation of the … WebIRF6 is a transcription factor that belongs to a family of nine transcription factors that share a highly conserved helix-turn-helix DNA-binding domain and a less conserved protein-binding domain. Most IRFs regulate the expression of interferon-alpha and -beta after viral infection, but the function of IRF6 is related to epidermal development. –
WebJun 11, 2024 · IRF6 is low-expressed and suppresses proliferation and differentiation in squamous cell carcinomas, such as nasopharyngeal and esophageal cancer, among others 16,17,18. IRF6 induces apoptosis in ... WebThe interferon regulatory factor 6 (IRF6) is functioned as a tumor suppressor gene in several cancers and is associated with risk of CRC. We explored the role of IRF6 in CRC in the present...
http://www.cancerindex.org/geneweb/IRF6.htm
WebMay 3, 2024 · Inhibition of KIF20A by transcription factor IRF6 affects the progression of renal clear cell carcinoma Abstract. Renal clear cell carcinoma (ccRCC) is one of the most … primary vs enabled adapterWebAug 8, 2024 · A 16E6 protein binding domain essential for p53 degradation played a crucial role in regulating IL-1β transcription. 16E6 blocked the p53 transcriptional regulation of Interferon Regulatory Factor 6 (IRF6), which we found was essential for … playful paws doggy daycareplayful pets conshohocken paWebRIPK4. Cr. La proteïna serina/treonina cinasa 4 d’interacció amb receptor o RIPK4 (acrònim de l’anglès Receptor-interacting serine/threonine-protein kinase 4) és un enzim codificat en els humans pel gen RIPK4, localitzat en el cromosoma 21. [4] Aquest enzim pertany a la família de les proteïnes quinases d’interacció amb receptor o ... playful paws league city txWebNov 15, 2024 · Figure 2 IRF6 and GRHL3 downregulation in cancer cell lines (A) Panels of cancer cell lines and corresponding normal cells (striped boxes) were screened for IRF6, … playful paws doggy daycare richmond bcWebNov 15, 2024 · Our data uncovered consistent downregulation of IRF6 and GRHL3 in all types of carcinomas analyzed. Reduced levels of IRF6 and GRHL3 were found to be associated with several tumorigenic properties, such as enhanced cell proliferation, epithelial mesenchymal transition, migration and reduced differentiation capacity. playful pets conshohockenWebJun 11, 2024 · Lin28A promotes IRF6-regulated aerobic glycolysis in glioma cells by stabilizing SNHG14 - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. Federal government websites often end in .gov or .mil. playful paws pet daycare jackson michigan