Cisplatin medication interactions
WebApr 14, 2024 · Huixin Tan. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of … WebSep 15, 2024 · The most common side effects of Cisplatin include: nausea, vomiting (may be severe), diarrhea, temporary hair loss, loss in ability to taste food, hiccups, dry mouth, …
Cisplatin medication interactions
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WebApr 14, 2024 · Since HK-2-cells-generated-Abs, both by cisplatin or upon UV light exposure, can induce apoptosis in HK-2 cells, the purpose of this work was to study their metabolome and therein find the molecular features which help us to unravel the mechanisms of that phenomenon. WebCisplatin Interaction with 94 drugs. Find out more in the list below: Acetyldigitoxin Acetyldigitoxin may decrease the cardiotoxic activities of Cisplatin. Aclarubicin Cisplatin may...
WebSep 1, 2024 · Cisplatin for injection can cause severe hypersensitivity reactions, including anaphylaxis and death. Manifestations have included facial edema, wheezing, … WebApr 19, 2024 · Anaphylactic-like reactions to PLATINOL have been reported. Facial edema, bronchoconstriction, tachycardia, and hypotension may occur within minutes of PLATINOL administration. Epinephrine, corticosteroids, and antihistamines have been effectively employed to alleviate symptoms (see WARNINGS and ADVERSE REACTIONS ).
WebFeb 26, 2024 · Common side effects may include: hearing problems; kidney problems; numbness or tingling; nausea, vomiting; or. bone marrow suppression. This is not … WebSep 24, 2024 · Cisplatin exerts anticancer activity via multiple mechanisms. Its most acceptable mechanism involves the formation of DNA–platinum adducts by interacting with purine bases, activating several signal transduction pathways, and silencing or activating several genes which finally leads to apoptosis.
WebMar 25, 2024 · AEG-1 (astrocyte elevated gene-1) promotes drug resistance by interfering with the ubiquitination and proteasomal degradation of MDR1 (multidrug resistance gene 1), thereby enhancing drug efflux. ... cisplatin resistance; interaction. Grant support 13-CX-3, 201409-202409/the Qingdao Startup and Innovation Leader Talent Plan 81472542/the ...
WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel … the principle of directness and verbalismWebkidney disease. low blood counts, like white cells, platelets, or red blood cells. tingling of the fingers or toes, or other nerve disorder. an unusual or allergic reaction to cisplatin, … the principle of diminishing returnsWebFeb 25, 2024 · Anaphylactic-like reactions to PLATINOL-AQ have been reported. Facial edema, bronchoconstriction, tachycardia, and hypotension may occur within minutes of PLATINOL-AQ administration. Epinephrine, corticosteroids, and antihistamines have been effectively employed to alleviate symptoms (see WARNINGS and ADVERSE … the principle of diversification tells usWebcisplatin in biological matrices. The ratios of cisplatin to total free (ultrafilterable) platinum in the plasma vary considerably between patients and range from 0.5 to 1.1 after a dose of 100 mg/m. 2 . Cisplatin does not undergo the instantaneous and reversible binding to plasma proteins that is characteristic of normal drug-protein binding. sigma gamma rho sorority inc 1922WebCisplatin may cause severe kidney problems, nerve problems, and severe nausea and vomiting. Nerve problems may occur during treatment or weeks after stopping treatment. … the principle of effective stress bishop 1959WebCisplatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: nausea vomiting diarrhea hair loss loss in ability to taste food hiccups … sigma gamma rho sorority inc founders dayWebcisplatin A total of 410 drugs are known to interact with cisplatin . Cisplatin is in the drug class alkylating agents . Cisplatin is used to treat the following conditions: Anal Cancer … the principle of diminishing returns applies