WebAnti-mouse CD31 clones 390 and MEC13.3 bind to their respective non-overlapping epitopes in IgD2 of CD31. 8 Additional reported applications (for the relevant formats) include: immunoprecipitation 1, in vitro and in vivo blocking of CD31-mediated cell-cell interactions 1-4, and immunohistochemical staining 5,6,7 of acetone-fixed frozen … WebMIBI: CD31 staining (cyan) of FFPE mouse ileum, costained with dsDNA (magenta) Background: CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), plays roles in leukocyte transmigration, angiogenesis, and integrin activation. Specifically, CD31 is highly expressed at endothelial cell-cell junctions, functioning as an ...
Protocol for Emulate Organ-Chips: Immunofluorescence …
WebCD31 is heavily glycosylated and glycosylation accounts for 40% of the mass of CD31. PECAM-1 appears to be able to interact both with itself in an homophilic interaction and with other molecules in an heterophilic interaction. ... CD31 immunohistochemical stain. A reduction in microvascular density, as revealed by a reduced number of CD31 ... WebThe MEC13.3 antibody specifically recognizes CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1). CD31 is a 130 kDa integral membrane protein, a member of the immunoglobulin superfamily, that mediates cell-to-cell adhesion. CD31 is expressed constitutively on the surface of adult and embryonic endothelial cells and is … the barberry contact number
Immunohistochemical Expression of Endothelial Markers CD31, …
WebAngiogenesis evaluated by α-SMA and CD31 staining. (A): Representative images of α-SMA and CD31 staining in peri-infarcted region at the endpoint in each group. Vessels … Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome17q23.3. PECAM-1 plays a key role in removing aged neutrophils from the body. See more PECAM-1 is a highly glycosylated protein with a mass of approximately 130 kDa. The structure of this protein was determined by molecular cloning in 1990, when it was found out that PECAM-1 has N-terminal domain … See more PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of See more • Jackson DE (April 2003). "The unfolding tale of PECAM-1". FEBS Letters. 540 (1–3): 7–14. doi:10.1016/S0014-5793(03)00224-2. PMID 12681475. S2CID 21470915 See more CD31 is normally found on endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, lymphocytes (T cells, B cells, and NK cells), megakaryocytes, and osteoclasts. See more Cancer PECAM-1 is expressed by many solid tumor cell lines such as hemangioma, angiosarcoma See more • Human CD Antigen Chart (eBioscience) • Mouse CD Antigen Chart (eBioscience) • Human PECAM1 genome location and PECAM1 gene details page in the UCSC Genome Browser. See more WebIHC staining for CD31 and PAS staining revealed VM, which was mostly detected in specimens with high TJP1 expression (Fig. 1 D). We also compared the expression levels within individual specimens and found that TJP1 expression was positively correlated with VM, with 50 (57%) out of 74 and 3 (4%) out of 13 specimens showing high expression of … the barberry centre